EnvisionTEC 3D-Bioplotter Family
There’s Only One 3D-Bioplotter®
Well, actually, EnvisionTEC has three.
But when medical researchers and manufacturers are talking about “the Bioplotter,” that’s a nod to EnvisionTEC's bioprinter technology. A recognized world leader in biofabrication, EnvisionTEC’s 3D-Bioplotter family is being used for groundbreaking medical research and manufacturing. Launched in 2000, the 3D-Bioplotter is the most seasoned bioprinter in the market, backed by the most research, more than 150 research papers to date.
The EnvisionTEC 3D-Bioplotter® Family:
more about the:
EnvisionTEC 3D-Bioplotter Family
Three Levels of Functionality
Starter, Developer and Manufacturer — this family of bioprinters, as shown below, processes open-source biomaterials using air or mechanical pressure to a syringe, which can fabricate scaffolds to create tissue, organs and more. Our bioprinters are extremely accurate with X-Y repeatability down to 1 μm. All models have been designed for use in a sterile biosafety cabinet, meet standards for clinical trials and offer build sizes up to 192.4 cubic inches.
Developed at the University of Freiburg, the bioprinting technology used by the 3D-Bioplotter allows for maximum flexibility for research and development. The system uses modular components, such as sterilized heating and cooling cartridges, standard Luer-Lok syringes with standard needle-tip sizes and an easy-to-use 365 nm UV curing head. “It’s a popular tool because it’s a very flexible, but also user-friendly machine,” Carlos explained. The software also allows for maximum freedom in combining different materials using different temperatures.
Many machine features vary between models. For example, the Manufacturer model allows for 5 print heads and also includes a heated platform and sterile filter, which is recommended for cell and organ printing.
The 3D-Bioplotter family is also made with high-quality components and is extremely reliable, allowing R&D to spend more time printing. Rahul Roy, a North American service and applications engineer and 3D-Bioplotter expert, credits the German engineering and manufacturing. The 3D-Bioplotter, he said, “is built like a battleship.”
Starter Series

The 3D-Bioplotter Starter Series is designed for research groups new to the field of tissue engineering with few requirements in parallel material processing and automation. It consists of the same basic hardware and software as the other two 3D-Bioplotter models, but lacks modular capability and platform temperature control. The 3D-Bioplotter Starter Series comes with 2 fixed high-temperature heads.
Machine Properties
- Build Volume (XYZ): 150 x 150 x 140 mm (5.91” x 5.91” x 5.51”)
- Speed: 0.1 – 150 mm/s (0.004” – 5.91”/s)
- Minimum Strand Diameter: 0.100 mm (0.004”) – Material Dependent
- Axis Resolution (XYZ): 0.001 mm (0.00004”)
- Filters Included: Particle
- Platform Temperature Control: No
- Max Heads: 2
- Head Temperature Range: High: 30° – 250°C (86° – 482°F)
- No. of Heads Included: 2
- Tool Changer Type: Fixed Side-By-Side Tools
- Cartridge Sizes: 3-30 ml (0.1 – 1.0 fl oz)
- Other Usable Modules: None
- Platform Height Control: Manual
- Needle Calibration: Photo Sensor
- Material Calibration: Manual
- External Temp. Ports: 0
- Included PC: Built-in PC
Primary Application
- Biofabrication
Developer Series

The 3D-Bioplotter Developer Series is designed for research groups new to the field of tissue engineering, as well as for specialized use, where limited capability may still meet requirements. It consists of the same basic hardware and software as the Manufacturer Series with reduced functionality regarding camera and park positions, but is still capable of using a UV curing head and an optional heated platform.
Machine Properties
- Build Volume (XYZ): 150 x 150 x 150 mm (5.91 x 5.91 x 5.51 in.)
- Speed: 0.1 – 150 mm/s (0.004 – 5.91 in/s)
- Minimum Strand Diameter: 0.100 mm (0.004 in.) Material Dependent
- Axis Resolution (XYZ): 0.001 mm (0.00004 in.)
- Filters Included: Particle and Sterile
- Platform Temperature Control: Yes (Chiller not included): -10° – 80°C (14° – 176°F)
- Max Heads: 3
- Head Temperature Range: Low: 0° – 70°C (32° – 158°F) or High: 30° – 250°C (86° – 482°F)
- No. of Heads Included: 2
- Tool Changer Type: Modular Tool Changer
- Cartridge Sizes: 10 – 30 ml (.3 – 1.0 fl oz)
- Other Usable Modules: All
- Platform Height Control: Automatic
- Needle Calibration: Photo Sensor
- Material Calibration: Manual
- External Temp. Ports: 0
- Included PC: Professional PC
Primary Application
- Biofabrication
Manufacturer Series

The 3D-Bioplotter System is a versatile rapid prototyping tool for processing a great variety of biomaterials for computer-aided tissue engineering (CATE), from 3D CAD models and patient CT data to the physical 3D scaffold with a designed and defined outer form and an open inner structure.
Manufacturer Series Includes
- Built-in camera to enhance needle calibration and to ensure consistent prints
- Temperature controlled build platform and sensor ports. This allows greater material variety and finely tuned environments for low tolerance scaffolding
- Five cartridges slots for more materials in a single print
Machine Properties
- Build Volume (XYZ): 150 x 150 x 150 mm (5.91 x 5.91 x 5.51 in.)
- Speed: 0.1 – 150 mm/s (0.004 – 5.91 in/s)
- Minimum Strand Diameter: 0.100 mm (0.004 in.) Material Dependent
- Axis Resolution (XYZ): 0.001 mm (0.00004 in.)
- Filters Included: Sterile and Particle
- Platform Temperature Control: Yes (Chiller Included): -10° – 80°C (15° – 176° F)
- Max Heads: 5
- Head Temperature Range: Low: 0° – 70°C (32° – 158°F) or High: 30° – 250°C (86° – 482°F)
- No. of Heads Included: 2
- Tool Changer Type: Modular Tool Changer
- Cartridge Sizes: 10 – 30 ml (.3 – 1.0 fl oz)
- Other Usable Modules: All
- Platform Height Control: Automatic
- Needle Calibration: Camera
- Material Calibration: Semi-automatic
- External Temp. Ports: 4
- Included PC: Professional PC
Primary Application
- Biofabrication